VENDAJE

Vendaje is a human connective tissue matrix comprised of amniotic tissue which is processed using our proprietary BioRetain process.
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This process creates a dehydrated human amniotic membrane (DHAM) allograft.
BioRetain®-the science of letting nature do its work.
VENDAJE is intended for homologous use as a protective covering.
Easy to Use—Easy to Store!
VENDAJE allografts:
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Are held in place via hydrostatic tension and may be used in an open incision or placed as a dermal substitute.
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Are aseptically processed and terminally sterilized via e-beam irradiation.
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Have a 5-year shelf life and can be stored at ambient temperatures.
Six steps work together to preserve the natural integrity of amniotic tissue:


A LOOK INSIDE VENDAJE


Natural Amniotic Components Retained in VENDAJE
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VENDAJE allografts are prepared using our proprietary BioRetain® process, which was designed to help preserve the natural ECM components, anti-inflammatory cytokines, and endogenous growth factors within fresh tissue.
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The following substances were isolated within VENDAJE allografts (n=6)*:
Anti-inflammatory cytokines:
– Interleukin (IL) 10
IL-10 helps suppress the pro-inflammatory milieu and modulate immunity through a variety of pathways.
– IL-1 receptor antagonist
This substance naturally inhibits pro-inflammatory effects of IL-1.
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Extracellular matrix (ECM) components:
– Collagens I, III, IV, V, and VI
– Elastin
– Laminin
– Fibronectin
– Proteoglycans
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The ECM of amniotic membrane provides mechanical protection and functional support for cell attachment, proliferation, and migration.

